Is there a place for Stem Cells in Aesthetic Medicine?
Skincare companies have been utilizing stem cells topically in their products; however, they are sourced from plants or bacteria. Because they are not derived from the human body they are not as easily recognized and this results in a less significant effect in the skin. The future of stem cells cosmetically will be the injection of it into our faces almost as commonly as Botox is today. Injected stem cells can replace tissue loss and provide a direct source for critical growth factors.
What are Growth Factors?
Growth factors are produced by the body to control growth, division and maturation of cells. They are what regulate the division and the production of cells.
Where do our Growth Factors come from?
We source our growth factors from adult stem cells that are derived from fat cells. These fat cells are harvested from the subcutaneous fat of healthy adult donors. Once harvested, the stem cells begin a growth cycle during which they generate growth factors.
Beginning Source:
Adult stem cells derived from fat cells.
Stem cells transferred to a culture containing specific growth media.
Stem cells begin dividing. During this process their
growth factors are secreted.
growth factors are secreted.
150-300 growth factors and *cytokines are
secreted from the division of stem cells.
We collect the growth factor secretions and leave the stem cells behind to continue division and secretion of growth factors.
*Cytokines work together with cells of the immune system in order to regulate the body's response to disease and infection. Cytokines also mediate normal cellular processes in the body.
What do Growth Factors do when used in skincare?
When growth factors are utilized in products they have two major benefits: protect the skin and stimulate growth of new cells. The growth factors that are secreted from adult human stem cells benefit all skin conditions. Take for example:
HGF (Hepatocyte Growth Factor)
enhances wound repair and increases the number of macrophages for scar tissue removal.
TGF-B (Transforming Growth Factor Beta)
increases new blood vessel formation and collagen production.
FGF (Fibroblast Growth Factor)
elevates the number of collagen manufacturing cells along with increasing their production levels.
IFNg (Interferon Gamma)
fights viral and bacterial infections and increases 'Natural Killer' cell activity.
PDGF-AA (Platelet Derived Growth Factor)
creates new fibroblasts, increases the number of macrophages, increases angiogenesis and new cell development.
Why do we choose to use Growth Factors?
We choose to use growth factors because we can obtain hundreds of them from stem cells, and when applied topically to the skin we can encourage multiple cell type growth to repair and replace damaged cells.
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